SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef350f89d032c9c97b7e650cb629863753d70621f5d608230fc5535024cf6e4' 
  AND token = 'VlcAoxFrZko4HrjI+L6YV++nbJMwRI4QYtoq1KcsWe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}