SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7463d7620e7498b4c72bb895412231ca7efcf272dfada7521c05976a43bc9cfa' 
  AND token = '+VWTP7KwHZ6DdLe5WwDX16vRvaWJjrfnqUBn2Cgkkbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}