SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5144d2fbf207255db4499d861eaa998ea7f1f255b8ddb5664e3060063f87694' 
  AND token = '8I3UjIauMH8S/WFjvO1W2kPHXbHjypSjX+SZ2fTmsgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}