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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e219e4adf1e807aee5d0e8d444c1893774b1c9202bc6ab1a96e8681099478f1' 
  AND token = 'AGDRQCmqu/n4s05BTaL37FEY99FOdsfQrJNFbWQZ3pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}