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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b189903db7b431552a045eb26860b1e4a81a1db950daf485c95a5480f97b915a' 
  AND token = 'UQ+miD/+6vU1fQVs2Za3I7stapLVzpfUJw//uaX8VFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}