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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc4fc3a7ef6f4b32ddf9b564d8557b1a9f768b8cd8689b45f13d0fdbbf591156' 
  AND token = 'uLsYqXJ6QTPegNOQDIsb8qTj7pIsqlSfF7xOFINUSLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}