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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad5f02acedb2a654b2c30a1c09372233685dc2059f0ff1faf41a9f4b515aa652' 
  AND token = 'Gqk85mBffQkDnOlv0MgsEqKmKUkPMvCAl+lOHMK/x5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}