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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7daab9fd25c8ee006dc781aa6572a9d046d0eadf2d3db292d1c80a77b39740cf' 
  AND token = 'ZrYbfPV+MDnqNCs8tiLRHUbOJ6V6dScyDAgiueCuDlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}