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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42869c04b9bd23c70760d4941fe46cf03e48f0aafd76e793184c34e51cb4a05c' 
  AND token = 'HSZSX0Xgqov+CNR6oa9bGHWV9Jvm7zGPD8ReG93I6AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}