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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a28f110ad3e0da0bb1f7b805cca733bdc36016381a1bcb3e44c742bd6714a2' 
  AND token = 'pzaahXHwQmCdViDwUwOeFHrunVC0siFBgNsPsu0d/vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}