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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16199118e211a5606edf2a044144a0b544d35f075f3c1372ad3f467f328dadab' 
  AND token = '+LznpmIn7fkgY4nmtXFmJKshihze4pODRC1utNeXee8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}