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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9378ab8fc5d93de04c2edb02f9d4fba998484a80e3a600b88f7fc665f52530f' 
  AND token = 'LnYfmWr/FjP9x2vrKKDlk0ffXO6LsnrPYzlTfN40jZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}