SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7a0d0b2ed6f3262d23a6df913c306c26b7afcb79c30da9499c3853a1805134' 
  AND token = 'MBvazZ3voP8zBxJhptJ0r22ZBbpcAVcohXmhedKv4cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}