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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bdb854cade1ba0f468212467cff58e8851b39c6384c9febfa4a05e82ad3834' 
  AND token = 'oc4KqyglL/gnZCGeOxT+yp8ACTPsXHA16GuqDe9BW/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}