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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdfec00552c2592109439485ab1b27e01e9ba8ad24c3ebd1f75e362e45594c03' 
  AND token = 'tq9k/EuWbW2XwDYs0iCta7oGPCbSagH0uKJdOkyq9+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}