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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aca7e9c57f3f5316c6b3160cff48801f2c715fcf8106014a6ddc7ffe65f4567' 
  AND token = '0Qu8YnqIbSaPB/QQuLQubTJt6APMB0fiFhEFIUMlGCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}