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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ea409b5493f21e76a249cac59c28d93d1b6c9268adbd05566dffb9702edacb' 
  AND token = 'rIqRF0Caf/jnZ6pcbfm1XyrkHInlx+dAThHCIj262Tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}