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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cda975e7d67429d3c10d1aa9844dc1eb0ca6b7e4b0c17ba182ed07dde01bd48' 
  AND token = '8VSjdshNCkmZDTpRMh2bih+iljlDLhgHKSnWlQzqaTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}