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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71d6bcc2d7aebcbc8c396fe3426ca18887a9b7aa1de4c05464476471fd642825' 
  AND token = 'ky4bEjOCpPPeuwi3F5hOr5cPYEItjCgGsBDEiP7D9Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}