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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '665c059f1091075f3b0b62b2f7579e41be576da778b29546b6a60f88a78ff884' 
  AND token = 'bnucv0d2S6RiPRWKPByvlhDNzAzzAjcsTq1BVwBYvN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}