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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35bd502a25be0af2171288dbd5020d7c45a2ec40b86aafb691d7e641ae599e44' 
  AND token = 'zG95ysmXPqk9I/oB607ZdgaAxSqRXzvrkI5d48wtHqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}