SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7349d25c2da609f5fd974cba488328b3697a1fed4050231fb07b84bdbc0902e6' 
  AND token = 'e0xT/PNDKHC4cK+emqhOCKOZyi8BclCFz3pe1UQKuBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}