SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c740cb5b165586ed2e58bf57d0a50b61d8d245f47f12a20330feb02d91d38e' 
  AND token = 'k7QaBjzs4MnuDmeU4HY8gzRyYV6N8TylQ3ewjl/eYZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}