SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9231fed30fce5bd0f8e621102df54a2a7ec703bb20465c625d996ff670847e3' 
  AND token = 'NtDC0KaxBeIzdc12oE97fByH2OkNiiL6svo1htnTB6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}