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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c7d2b4826025f4b8216516a8f5b26c1a5e30981d7a655defeda0d1e25538249' 
  AND token = 'bDQhnax+NWD7mT6pO2vaAK456YAVr/kKd908YhUHA0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}