SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe4ef00572e0fc32db06173dab600eb656e0da55d6818ba3d52d149d94acde6' 
  AND token = 'EWa6FnHL7ir5cLViPh87iKqGtoY/zYshoL6SkckkXhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}