SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8112e5ee3b03f4c36e827c6f227fd5e821c0491106269e0f49359a3d27531f5' 
  AND token = 'ZnZRG41VX8TeaJTNnKojtVN0Pr6gka0BuCDyvZHSm40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}