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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4539008d86f235c922d68b57c456b6d7a4cbfbc44f4ef9d2be18709dc50cdfb' 
  AND token = 'RpIPlIUI7rUrsQNvr3/scKv4vV19dBM2a3Cxy71LRbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}