SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3cc0a71e76db7676352bf957a42a23a24e9d746cea8de5d3e285402dc9d672c' 
  AND token = 'rSknGyNaRWNUJZtHvFE8dbHg6844ZYCShTS5hyWgt/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}