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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e456712e2df8498c0775896d19151638b56253e1ea3948eae2734c8f56a7874c' 
  AND token = 'TQ7Gkeyvlh45L/hqDYdksoCsEFkbQ2eu3S139Xzf2lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}