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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153f2b5ff2e316ead460c39c4b5f98da6083703ce62feb33c72dd76c8deb0218' 
  AND token = 'b63w0wYOH+naFftYlC1XDGDjEnhHevYLPpP5uJA2S/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}