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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a87c3b7c4b6aaf363242c0035b538dcdb77711b55c0a30c74c340d306be280c' 
  AND token = 'M0OTlm0QJxCnEcniM0SD7vwJdntS3pK4SgKY2TumdjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}