SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9f365f5883197728bad4ac0039274bedf41142924b56a430dc1ee9dca34a8bc' 
  AND token = 'GXOSbGT2KrFN4qP+4YVMR/+JYTUgVtm9azhvkXLo5cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}