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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4374b8b91dd25be8eb24d73d84d65d88c885f4d93846cfa70e846e7b4f9c08e2' 
  AND token = 'y1JOEcJc82EUrcRAp+Gm2U0hNZLpQ4Ozj3PqZDUt2IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}