SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee2b63f4880e2e70ddfd1b528889ab7dff31736b5090a1a46ca1042fbcb5073b' 
  AND token = 'PueNsTpX9iCLGXTp5FsfR848PbFtcnOjsWbBfMxq/MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}