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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539de0e7e3f10cf032d272ca63674cb09e0935d18aab04cd091df30b0c5baa3f' 
  AND token = '+kZz8TojmQbORh1RC6RlcSuC9fU+rg/ngU1hdyB+HNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}