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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ce9dff9c9bad2da10a773054567245de432432bdf7e7fe67d28560ec4bb720' 
  AND token = '0oLUmhAZBIKX1K2dncOsGOjdMcwjvwyeXpI9ZhnTe/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}