SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac44fead84212584ef969caa9ca08958edee3166502cf6da55d1f182bcb5c25' 
  AND token = '1uceExWe44rle+qkbbd34N64TeS1i97KrYtzrJ+ENqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}