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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce256661390722b1f1412225285ea22a2b923afd5ea1d1b7efe1764f8a8ebc12' 
  AND token = 'hpr9A00UqZk0+JVov8iNkNHotCQfUAsGTX8ZmlHZqDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}