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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d57b6e42e721f1bc0ba1a93b665a2ed9cdd22cb85d3c20e2529faf95cd7668' 
  AND token = '4+3VaxMoMI+nR/aUJLHToBhU9vEA5P5sRmolbh75zKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}