SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24af4f4303a9a866d5c14425431d0a734ce16ff410edc0d4acbbcffe132d0f48' 
  AND token = 'IadonF7SD1Ap0VZlOXD3OPB9QTj7qiU2Q+pYl+76EOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}