SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bee166f59d13036d9e4a8032a3193e13558058548e673683d1228e01d54ce84' 
  AND token = 'OMUVo/IFSe0lC5wwfolQNxMSLqd2Lz0JMgbs2lmAHS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}