SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cc1027cb3a5a5975b9481bc9bc9e7e6a11984432059133c201536f8a3891ef' 
  AND token = 'ibz8g9f93VduJvxhlXUW78X216Zhr2zdoBqJAtgyDMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}