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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac9285da5441ec46970c1a8e437691b46f404499645456d87920f8bfecacc34' 
  AND token = 'GOIU0NI0wDMy3NQqrqhkF50DZc9fX+/ajUyV4dGTgjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}