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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29c4f3c47bc6db1c528c07b2be7d8731b846884cf45ef905a26364372e552713' 
  AND token = 'QDYbVTMfRfZaF5jdk7CbgwQSSCnGjwLD5iHU3zGXHT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}