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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa6ef2215d0d19865e6f5bc53decb15dcd8e650e3dbe6e3cdf3e9489020f7d43' 
  AND token = 'Iz5LExfSp/vNUwPmFD26UgJv7MYyjzl0rEANzBG4WL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}