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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa050fb5e92d7226a41f9276673a20b1bb06789531fa012f4d89d2dce9b1928' 
  AND token = 'MUtUEuAE70F26BTUyvXygqAiqd60Y8VAGeBodzt2Xug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}