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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96c8bc4f8b99e57bd28d31ea6edb3cf22af1cc8c8850e7f09d4e165698de92be' 
  AND token = 'nTqCwm0dx4ikSSzhDxD8rVK5Tnktp+0lUHD4cOjD1oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}