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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6867c1fcd0bc933e243cc8eb78aac168063c871f7985e4651a2c43de72b0e483' 
  AND token = 'UKJ1zT7+CIkmNEA4i7Z0pVPCYWYR2o6GlAz8noROPw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}