SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40f68d76c5b5415f4efdfbc9387e2654c87f0ea393b6f4c15d150c3f4e363fa5' 
  AND token = 'm/x4S2xVgOnpny/r7imzDNpz3+XqDsV6WaB93jh3Lmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}